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Rational screening of oligonucleotide combinatorial libraries for drug discovery.
Combinatorial strategies offer the potential to generate and screen extremely large numbers of compounds and to identify individual molecules with a desired binding specificity or pharmacological activity. We describe a combinatorial strategy for oligonucleotides in which the library is generated an...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1993
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309424/ https://ncbi.nlm.nih.gov/pubmed/7684128 |
| Oznake: |
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