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Chaperone proteins as single component reagents to assess antibody nonspecificity
Early stage assays that evaluate monoclonal antibody drug-like properties serve as valuable tools for selection of lead candidates. One liability for clinical development, off-target reactivity, is often assessed by binding to a mixture or panel of noncognate proteins. While robust, these mixes are...
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| Publicado no: | MAbs |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627595/ https://ncbi.nlm.nih.gov/pubmed/28745541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1356529 |
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