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Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles
A number of neurodegenerative disorders may potentially be treated by the delivery of therapeutic genes to neurons. Nonviral gene delivery systems, however, typically provide low transfection efficiency in post-mitotic differentiated neurons. To uncover mechanistic reasons for this observation, we c...
Enregistré dans:
| Publié dans: | Biomaterials |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737930/ https://ncbi.nlm.nih.gov/pubmed/16769110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2006.05.013 |
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