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Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

Mucus is a viscoelastic and adhesive gel that protects the lung airways, gastrointestinal (GI) tract, vagina, eye and other mucosal surfaces. Most foreign particulates, including conventional particle-based drug delivery systems, are efficiently trapped in human mucus layers by steric obstruction an...

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Main Authors: Lai, Samuel K., Wang, Ying-Ying, Hanes, Justin
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667119/
https://ncbi.nlm.nih.gov/pubmed/19133304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2008.11.002
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