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Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
Mucus is a viscoelastic and adhesive gel that protects the lung airways, gastrointestinal (GI) tract, vagina, eye and other mucosal surfaces. Most foreign particulates, including conventional particle-based drug delivery systems, are efficiently trapped in human mucus layers by steric obstruction an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667119/ https://ncbi.nlm.nih.gov/pubmed/19133304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2008.11.002 |
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