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Mucus-Penetrating Nanoparticles for Vaginal Drug Delivery Protect Against Herpes Simplex Virus

Incomplete coverage and short duration of action limit the effectiveness of vaginally administered drugs, including microbicides for preventing sexually transmitted infections. We investigated vaginal distribution, retention, and safety of nanoparticles with surfaces modified to enhance transport th...

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Détails bibliographiques
Auteurs principaux: Ensign, Laura M., Tang, Benjamin C., Wang, Ying-Ying, Tse, Terence A., Hoen, Timothy, Cone, Richard, Hanes, Justin
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817739/
https://ncbi.nlm.nih.gov/pubmed/22700955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003453
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