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Mucus-Penetrating Nanoparticles for Vaginal Drug Delivery Protect Against Herpes Simplex Virus

Incomplete coverage and short duration of action limit the effectiveness of vaginally administered drugs, including microbicides for preventing sexually transmitted infections. We investigated vaginal distribution, retention, and safety of nanoparticles with surfaces modified to enhance transport th...

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Detalhes bibliográficos
Main Authors: Ensign, Laura M., Tang, Benjamin C., Wang, Ying-Ying, Tse, Terence A., Hoen, Timothy, Cone, Richard, Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817739/
https://ncbi.nlm.nih.gov/pubmed/22700955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003453
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