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Oral Drug Delivery with Polymeric Nanoparticles: The Gastrointestinal Mucus Barriers

Oral delivery is the most common method for drug administration. However, poor solubility, stability, and bioavailability of many drugs make achieving therapeutic levels via the gastrointestinal (GI) tract challenging. Drug delivery must overcome numerous hurdles, including the acidic gastric enviro...

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Detalhes bibliográficos
Main Authors: Ensign, Laura M., Cone, Richard, Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322271/
https://ncbi.nlm.nih.gov/pubmed/22212900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2011.12.009
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