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Avoiding a sticky situation: bypassing the mucus barrier for improved local drug delivery
The efficacy of drugs administered by traditional routes is limited by numerous biological barriers that preclude reaching the intended site of action. Further, full body systemic exposure leads to dose-limiting, off-target side effects. Topical formulations may provide more efficacious drug and nuc...
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| Gepubliceerd in: | Trends Mol Med |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087626/ https://ncbi.nlm.nih.gov/pubmed/33414070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2020.12.001 |
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