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Non-degradative Intracellular Trafficking of Highly Compacted Polymeric DNA Nanoparticles

Highly compacted DNA nanoparticles (DNPs) composed of polyethylene glycol linked to a 30-mer of poly-L-lysine via a single cysteine residue (CK(30)PEG) have previously been shown to provide efficient gene delivery to the brain, eyes and lungs. In this study, we used a combination of flow cytometry,...

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Detalhes bibliográficos
Main Authors: Kim, Anthony J., Boylan, Nicholas J., Suk, Jung Soo, Lai, Samuel K., Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294172/
https://ncbi.nlm.nih.gov/pubmed/22079809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.031
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