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Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma
Complex genetic mutations are common in brain cancer, making gene therapy an attractive approach to repair or modulate altered genes and cellular pathways. Non-viral gene vectors can offer DNA delivery without the risk of immunogenicity and/or insertional mutagenesis that are common with viral vecto...
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| Publicado no: | J Mater Chem B Mater Biol Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254827/ https://ncbi.nlm.nih.gov/pubmed/25485114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4TB00559G |
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