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Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation
Highly compacted DNA nanoparticles, composed of single molecules of plasmid DNA compacted with block copolymers of poly-L-lysine and 10 kDa polyethylene glycol (CK(30)PEG(10k)), mediate effective gene delivery to the brain, eyes and lungs in vivo. Nevertheless, we found that CK(30)PEG(10k) DNA nanop...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245330/ https://ncbi.nlm.nih.gov/pubmed/21903145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.08.031 |
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