Topical ocular delivery to laser-induced choroidal neovascularization by dual internalizing RGD and TAT peptide-modified nanoparticles

A nanoparticle (NP) was developed to target choroidal neovascularization (CNV) via topical ocular administration. The NPs were prepared through conjugation of internalizing arginine-glycine-aspartic acid RGD (iRGD; Ac-CCRGDKGPDC) and transactivated transcription (TAT) (RKKRRQRRRC) peptide to polymer...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Chu, Yongchao, Chen, Ning, Yu, Huajun, Mu, Hongjie, He, Bin, Hua, Hongchen, Wang, Aiping, Sun, Kaoxiang
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2017
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325139/
https://ncbi.nlm.nih.gov/pubmed/28260884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S126865
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