PEGylation of nanoparticles improves their cytoplasmic transport

The efficacy of nucleus-targeted drug- or gene-carrying nanoparticles may be limited by slow transport through the molecularly crowded cytoplasm following endosome escape. Cytoskeletal elements and cellular organelles may pose steric and/or adhesive obstacles to the efficient intracellular transport...

Full description

Saved in:
Bibliographic Details
Main Authors: Suh, Junghae, Choy, Kok-Leong, Lai, Samuel K, Suk, Jung Soo, Tang, Benjamin C, Prabhu, Sudhir, Hanes, Justin
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2007
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676827/
https://ncbi.nlm.nih.gov/pubmed/18203439
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items