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Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine

AIMS: Sputum poses a critical diffusional barrier that strongly limits the efficacy of drug and gene carriers in the airways of individuals with cystic fibrosis (CF). Previous attempts to enhance particle penetration of CF sputum have focused on either reducing its barrier properties via mucolytics,...

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Autori principali: Suk, Jung Soo, Lai, Samuel K, Boylan, Nicholas J, Dawson, Michelle R, Boyle, Michael P, Hanes, Justin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102009/
https://ncbi.nlm.nih.gov/pubmed/21385138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.123
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