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Influence of DNA sequence on the structure of minicircles under torsional stress

The sequence dependence of the conformational distribution of DNA under various levels of torsional stress is an important unsolved problem. Combining theory and coarse-grained simulations shows that the DNA sequence and a structural correlation due to topology constraints of a circle are the main f...

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Publicat a:Nucleic Acids Res
Autors principals: Wang, Qian, Irobalieva, Rossitza N., Chiu, Wah, Schmid, Michael F., Fogg, Jonathan M., Zechiedrich, Lynn, Pettitt, B. Montgomery
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737869/
https://ncbi.nlm.nih.gov/pubmed/28609782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx516
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