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Influence of DNA sequence on the structure of minicircles under torsional stress

The sequence dependence of the conformational distribution of DNA under various levels of torsional stress is an important unsolved problem. Combining theory and coarse-grained simulations shows that the DNA sequence and a structural correlation due to topology constraints of a circle are the main f...

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Publicado en:Nucleic Acids Res
Autores principales: Wang, Qian, Irobalieva, Rossitza N., Chiu, Wah, Schmid, Michael F., Fogg, Jonathan M., Zechiedrich, Lynn, Pettitt, B. Montgomery
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737869/
https://ncbi.nlm.nih.gov/pubmed/28609782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx516
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