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Modeling DNA Thermodynamics under Torsional Stress

Negatively twisted DNA is essential to many biological functions. Due to torsional stress, duplex DNA can have local, sequence-dependent structural defects. In this work, a thermodynamic model of DNA was built to qualitatively predict the local sequence-dependent mechanical instabilities under torsi...

詳細記述

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書誌詳細
主要な著者: Wang, Qian, Pettitt, B. Montgomery
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026789/
https://ncbi.nlm.nih.gov/pubmed/24606942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.022
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