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Modeling DNA Thermodynamics under Torsional Stress
Negatively twisted DNA is essential to many biological functions. Due to torsional stress, duplex DNA can have local, sequence-dependent structural defects. In this work, a thermodynamic model of DNA was built to qualitatively predict the local sequence-dependent mechanical instabilities under torsi...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026789/ https://ncbi.nlm.nih.gov/pubmed/24606942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.022 |
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