Influence of DNA sequence on the structure of minicircles under torsional stress

The sequence dependence of the conformational distribution of DNA under various levels of torsional stress is an important unsolved problem. Combining theory and coarse-grained simulations shows that the DNA sequence and a structural correlation due to topology constraints of a circle are the main f...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Wang, Qian, Irobalieva, Rossitza N., Chiu, Wah, Schmid, Michael F., Fogg, Jonathan M., Zechiedrich, Lynn, Pettitt, B. Montgomery
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Computational Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737869/
https://ncbi.nlm.nih.gov/pubmed/28609782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx516
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