A Sensitive In Vitro High-Throughput Screen to Identify Pan-Filoviral Replication Inhibitors Targeting the VP35-NP Interface

The 2014 Ebola outbreak in West Africa, the largest outbreak on record, highlighted the need for novel approaches to therapeutics targeting Ebola virus (EBOV). Within the EBOV replication complex, the interaction between polymerase co-factor, viral protein 35 (VP35), and nucleoprotein (NP) is critic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Liu, Gai, Nash, Peter J., Johnson, Britney, Pietzsch, Colette, Ilagan, Ma. Xenia G., Bukreyev, Alexander, Basler, Christopher F., Bowlin, Terry L., Moir, Donald T., Leung, Daisy W., Amarasinghe, Gaya K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735849/
https://ncbi.nlm.nih.gov/pubmed/28152588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00209
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados