Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy

INTRODUCTION: IgA nephropathy is a chronic renal disease characterized by mesangial immunodeposits that contain autoantigen, which is aberrantly glycosylated IgA1 with some hinge-region O-glycans deficient in galactose. Macroscopic hematuria during an upper respiratory tract infection is common amon...

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Enregistré dans:
Détails bibliographiques
Publié dans:Kidney Int Rep
Auteurs principaux: Yamada, Koshi, Huang, Zhi-Qiang, Raska, Milan, Reily, Colin, Anderson, Joshua C., Suzuki, Hitoshi, Ueda, Hiroyuki, Moldoveanu, Zina, Kiryluk, Krzysztof, Suzuki, Yusuke, Wyatt, Robert J., Tomino, Yasuhiko, Gharavi, Ali G., Weinmann, Amy, Julian, Bruce A., Willey, Christopher D., Novak, Jan
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Translational Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733772/
https://ncbi.nlm.nih.gov/pubmed/29270528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2017.07.002
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