Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy

INTRODUCTION: IgA nephropathy is a chronic renal disease characterized by mesangial immunodeposits that contain autoantigen, which is aberrantly glycosylated IgA1 with some hinge-region O-glycans deficient in galactose. Macroscopic hematuria during an upper respiratory tract infection is common amon...

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Dades bibliogràfiques
Publicat a:Kidney Int Rep
Autors principals: Yamada, Koshi, Huang, Zhi-Qiang, Raska, Milan, Reily, Colin, Anderson, Joshua C., Suzuki, Hitoshi, Ueda, Hiroyuki, Moldoveanu, Zina, Kiryluk, Krzysztof, Suzuki, Yusuke, Wyatt, Robert J., Tomino, Yasuhiko, Gharavi, Ali G., Weinmann, Amy, Julian, Bruce A., Willey, Christopher D., Novak, Jan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Translational Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733772/
https://ncbi.nlm.nih.gov/pubmed/29270528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2017.07.002
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