Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy

INTRODUCTION: IgA nephropathy is a chronic renal disease characterized by mesangial immunodeposits that contain autoantigen, which is aberrantly glycosylated IgA1 with some hinge-region O-glycans deficient in galactose. Macroscopic hematuria during an upper respiratory tract infection is common amon...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Kidney Int Rep
Prif Awduron: Yamada, Koshi, Huang, Zhi-Qiang, Raska, Milan, Reily, Colin, Anderson, Joshua C., Suzuki, Hitoshi, Ueda, Hiroyuki, Moldoveanu, Zina, Kiryluk, Krzysztof, Suzuki, Yusuke, Wyatt, Robert J., Tomino, Yasuhiko, Gharavi, Ali G., Weinmann, Amy, Julian, Bruce A., Willey, Christopher D., Novak, Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2017
Pynciau:
Translational Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733772/
https://ncbi.nlm.nih.gov/pubmed/29270528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2017.07.002
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