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Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy

INTRODUCTION: IgA nephropathy is a chronic renal disease characterized by mesangial immunodeposits that contain autoantigen, which is aberrantly glycosylated IgA1 with some hinge-region O-glycans deficient in galactose. Macroscopic hematuria during an upper respiratory tract infection is common amon...

詳細記述

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書誌詳細
出版年:Kidney Int Rep
主要な著者: Yamada, Koshi, Huang, Zhi-Qiang, Raska, Milan, Reily, Colin, Anderson, Joshua C., Suzuki, Hitoshi, Ueda, Hiroyuki, Moldoveanu, Zina, Kiryluk, Krzysztof, Suzuki, Yusuke, Wyatt, Robert J., Tomino, Yasuhiko, Gharavi, Ali G., Weinmann, Amy, Julian, Bruce A., Willey, Christopher D., Novak, Jan
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733772/
https://ncbi.nlm.nih.gov/pubmed/29270528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2017.07.002
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