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Advanced glycation end products impair NLRP3 inflammasome–mediated innate immune responses in macrophages
Advanced glycation end products (AGEs) are adducts formed on proteins by glycation with reducing sugars, such as glucose, and tend to form and accumulate under hyperglycemic conditions. AGE accumulation alters protein function and has been implicated in the pathogenesis of many degenerative diseases...
Zapisane w:
| Wydane w: | J Biol Chem |
|---|---|
| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5733583/ https://ncbi.nlm.nih.gov/pubmed/29051224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806307 |
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