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Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation

Paclitaxel is a chemotherapeutic drug commonly used to treat different types of cancer. In addition to its antitumor effect, paclitaxel is also known to promote Toll-like receptor (TLR) 4-dependent inflammatory responses, which may lower its chemotherapeutic efficacy. However, it remains unclear whe...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Son, Seunghwan, Shim, Do-Wan, Hwang, Inhwa, Park, Jong-Hwan, Yu, Je-Wook
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532018/
https://ncbi.nlm.nih.gov/pubmed/31156650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01108
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