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Defective mitochondrial fission augments NLRP3 inflammasome activation

Despite the fact that deregulated NLRP3 inflammasome activation contributes to the pathogenesis of chronic inflammatory or metabolic disorders, the underlying mechanism by which NLRP3 inflammasome signaling is initiated or potentiated remains poorly understood. Much attention is being paid to mitoch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Sangjun, Won, Ji-Hee, Hwang, Inhwa, Hong, Sujeong, Lee, Heung Kyu, Yu, Je-Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614538/
https://ncbi.nlm.nih.gov/pubmed/26489382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15489
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