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Nontranscriptional regulation of NLRP3 inflammasome signaling by IL-4

Th2 cytokine IL-4 has been previously shown to suppress the production of proinflammatory cytokines in monocytes. However, the underlying molecular mechanism by which IL-4 signaling antagonizes proinflammatory responses is poorly characterized. In particular, whether IL-4 can modulate inflammasome s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunol Cell Biol
Hauptverfasser: Hwang, Inhwa, Yang, Jungmin, Hong, Sujeong, Lee, Eun Ju, Lee, Seung-Hyo, Fernandes-Alnemri, Teresa, Alnemri, Emad S, Yu, Je-Wook
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496256/
https://ncbi.nlm.nih.gov/pubmed/25601272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2014.125
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