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MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra (SN) and the reduction of dopamine levels in the striatum. Although details of the molecular mechanisms underlying dopaminergic neuronal death in PD rema...
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| Publicat a: | Cell Death Differ |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329843/ https://ncbi.nlm.nih.gov/pubmed/29786072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0124-5 |
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