Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation

Mitochondrial dysfunction is considered crucial for NLRP3 inflammasome activation partly through its release of mitochondrial toxic products, such as mitochondrial reactive oxygen species (mROS) and mitochondrial DNA (mtDNA). Although previous studies have shown that classical NLRP3-activating stimu...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Won, Ji-Hee, Park, Sangjun, Hong, Sujeong, Son, Seunghwan, Yu, Je-Wook
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646374/
https://ncbi.nlm.nih.gov/pubmed/26416893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.667063
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