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Advanced glycation end products impair NLRP3 inflammasome–mediated innate immune responses in macrophages
Advanced glycation end products (AGEs) are adducts formed on proteins by glycation with reducing sugars, such as glucose, and tend to form and accumulate under hyperglycemic conditions. AGE accumulation alters protein function and has been implicated in the pathogenesis of many degenerative diseases...
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| Gepubliceerd in: | J Biol Chem |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5733583/ https://ncbi.nlm.nih.gov/pubmed/29051224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806307 |
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