Paclitaxel Enhances the Innate Immunity by Promoting NLRP3 Inflammasome Activation in Macrophages

Microtubules play critical roles in regulating the activation of NLRP3 inflammasome and microtubule-destabilizing agents such as colchicine have been shown to suppress the activation of this inflammasome. However, it remains largely unknown whether paclitaxel, a microtubule-stabilizing agent being u...

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Udgivet i:Front Immunol
Main Authors: Zeng, Qiong-zhen, Yang, Fan, Li, Chen-guang, Xu, Li-hui, He, Xian-hui, Mai, Feng-yi, Zeng, Chen-ying, Zhang, Cheng-cheng, Zha, Qing-bing, Ouyang, Dong-yun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361797/
https://ncbi.nlm.nih.gov/pubmed/30761140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00072
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