Evodiamine Augments NLRP3 Inflammasome Activation and Anti-bacterial Responses Through Inducing α-Tubulin Acetylation

Evodiamine is a major ingredient of the plant Evodia rutaecarpa, which has long been used for treating infection-related diseases including diarrhea, beriberi and oral ulcer, but the underlying mechanism is unclear. Here we aimed to explore whether evodiamine influenced NLRP3 (NLR family, pyrin cont...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Chen-Guang, Zeng, Qiong-Zhen, Chen, Ming-Ye, Xu, Li-Hui, Zhang, Cheng-Cheng, Mai, Feng-Yi, Zeng, Chen-Ying, He, Xian-Hui, Ouyang, Dong-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443907/
https://ncbi.nlm.nih.gov/pubmed/30971927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00290
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