Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis

The NLRP3 inflammasome plays a critical role in mediating the innate immune defense against pathogenic infections, but aberrant activation of NLRP3 inflammasome has been linked to a variety of inflammatory diseases. Thus targeting the NLRP3 inflammasome represents a promising therapeutic for the tre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Liu, Yi, Jing, Yan-Yun, Zeng, Chen-Ying, Li, Chen-Guang, Xu, Li-Hui, Yan, Liang, Bai, Wen-Jing, Zha, Qing-Bing, Ouyang, Dong-Yun, He, Xian-Hui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767189/
https://ncbi.nlm.nih.gov/pubmed/29375379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00975
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg