Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly

Autophagy and NLRP3 inflammasome were associated with the process of colitis. Drugs targeting NLRP3 inflammasome and autophagy to treat colitis are absent, and they are urgently required. Herein, we examine the effect of evodiamine, extracted from the fruit of Evodiae Fructus, on experimental coliti...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ding, Wenwen, Ding, Zhiquan, Wang, Yong, Zhu, Yan, Gao, Qi, Cao, Wangsen, Du, Ronghui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681073/
https://ncbi.nlm.nih.gov/pubmed/33240089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.573870
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