Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly

Autophagy and NLRP3 inflammasome were associated with the process of colitis. Drugs targeting NLRP3 inflammasome and autophagy to treat colitis are absent, and they are urgently required. Herein, we examine the effect of evodiamine, extracted from the fruit of Evodiae Fructus, on experimental coliti...

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Publicat a:Front Pharmacol
Autors principals: Ding, Wenwen, Ding, Zhiquan, Wang, Yong, Zhu, Yan, Gao, Qi, Cao, Wangsen, Du, Ronghui
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681073/
https://ncbi.nlm.nih.gov/pubmed/33240089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.573870
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