Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly

Autophagy and NLRP3 inflammasome were associated with the process of colitis. Drugs targeting NLRP3 inflammasome and autophagy to treat colitis are absent, and they are urgently required. Herein, we examine the effect of evodiamine, extracted from the fruit of Evodiae Fructus, on experimental coliti...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Ding, Wenwen, Ding, Zhiquan, Wang, Yong, Zhu, Yan, Gao, Qi, Cao, Wangsen, Du, Ronghui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681073/
https://ncbi.nlm.nih.gov/pubmed/33240089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.573870
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