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Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis

Multiple sclerosis (MS) is a chronic autoimmune and degenerative disease of the central nervous system, and conventional treatments have limited efficacy or side effects. Ghrelin, a 28-amino acid octanoylated peptide, has been reported to have neuroprotective effects, including anti-oxidation, anti-...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Liu, Fei, Li, Zijian, He, Xin, Yu, Haiyang, Feng, Juan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851267/
https://ncbi.nlm.nih.gov/pubmed/31780940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01320
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