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NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis

The NLRP3 inflammasome is a multiprotein complex consisting of three kinds of proteins, NLRP3, ASC, and pro-caspase-1, and plays a role in sensing pathogens and danger signals in the innate immune system. The NLRP3 inflammasome is thought to be involved in the development of experimental autoimmune...

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Detalhes bibliográficos
Main Authors: Inoue, Makoto, Williams, Kristi L., Gunn, Michael D., Shinohara, Mari L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387125/
https://ncbi.nlm.nih.gov/pubmed/22699511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201836109
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