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IFNβ therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome
Interferon-β (IFN-β) is widely used to treat multiple sclerosis (MS), and its efficacy was demonstrated in the setting of experimental autoimmune encephalomyelitis (EAE), an animal model of MS; however, IFN-β is not effective in treating all cases of MS. Here, we demonstrate that signaling by IFNAR...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509177/ https://ncbi.nlm.nih.gov/pubmed/22623753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002767 |
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