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Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury

Cisplatin (cis-Diamminedichloroplatinum II) has been widely and effectively used in chemotherapy against tumors. Nephrotoxicity due to cisplatin is one of the most common clinical causes of acute kidney injury (AKI), which has a poor prognosis and high mortality. The signaling mechanisms underlying...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Jun, Fan, Youling, Tang, Simin, Wu, Huiping, Zhong, Jiying, Huang, Zhengxing, Yang, Chengxiang, Chen, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732719/
https://ncbi.nlm.nih.gov/pubmed/29262553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20790
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