Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury

Cisplatin (cis-Diamminedichloroplatinum II) has been widely and effectively used in chemotherapy against tumors. Nephrotoxicity due to cisplatin is one of the most common clinical causes of acute kidney injury (AKI), which has a poor prognosis and high mortality. The signaling mechanisms underlying...

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Udgivet i:Oncotarget
Main Authors: Zhou, Jun, Fan, Youling, Tang, Simin, Wu, Huiping, Zhong, Jiying, Huang, Zhengxing, Yang, Chengxiang, Chen, Hongtao
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732719/
https://ncbi.nlm.nih.gov/pubmed/29262553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20790
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