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Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury

Cisplatin (cis-Diamminedichloroplatinum II) has been widely and effectively used in chemotherapy against tumors. Nephrotoxicity due to cisplatin is one of the most common clinical causes of acute kidney injury (AKI), which has a poor prognosis and high mortality. The signaling mechanisms underlying...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhou, Jun, Fan, Youling, Tang, Simin, Wu, Huiping, Zhong, Jiying, Huang, Zhengxing, Yang, Chengxiang, Chen, Hongtao
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732719/
https://ncbi.nlm.nih.gov/pubmed/29262553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20790
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