Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury

Cisplatin (cis-Diamminedichloroplatinum II) has been widely and effectively used in chemotherapy against tumors. Nephrotoxicity due to cisplatin is one of the most common clinical causes of acute kidney injury (AKI), which has a poor prognosis and high mortality. The signaling mechanisms underlying...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Zhou, Jun, Fan, Youling, Tang, Simin, Wu, Huiping, Zhong, Jiying, Huang, Zhengxing, Yang, Chengxiang, Chen, Hongtao
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732719/
https://ncbi.nlm.nih.gov/pubmed/29262553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20790
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