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Pharmacological Inhibition of PTEN Aggravates Acute Kidney Injury

Renal ischemia/reperfusion is a major cause of acute kidney injury. However, the pathogenic mechanisms underlying renal ischemia/reperfusion injury (IRI) are not fully defined. Here, we investigated the role of PTEN, a dual protein/lipid phosphatase, in the development of ischemic AKI in mice. Pharm...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Zhou, Jun, Jia, Li, Hu, Zhaoyong, Wang, Yanlin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572703/
https://ncbi.nlm.nih.gov/pubmed/28842716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10336-8
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