Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy

In diabetic nephropathy (DN), podocyte cytoskeletal rearrangement occurs followed by podocyte effacement and the development of proteinuria. PTEN (phosphatase and tensin homolog) is a ubiquitously expressed phosphatase that plays a critical role in cell proliferation, cytoskeletal rearrangement and...

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Bibliografske podrobnosti
izdano v:J Pathol
Main Authors: Lin, Jamie, Shi, Yuanyuan, Peng, Hui, Shen, Xiaojie, Thomas, Sandhya, Wang, Yanlin, Truong, Luan D., Dryer, Stuart E, Hu, Zhaoyong, Xu, Jing
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398628/
https://ncbi.nlm.nih.gov/pubmed/25641678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4508
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