Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy

In diabetic nephropathy (DN), podocyte cytoskeletal rearrangement occurs followed by podocyte effacement and the development of proteinuria. PTEN (phosphatase and tensin homolog) is a ubiquitously expressed phosphatase that plays a critical role in cell proliferation, cytoskeletal rearrangement and...

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Bibliographic Details
Published in:J Pathol
Main Authors: Lin, Jamie, Shi, Yuanyuan, Peng, Hui, Shen, Xiaojie, Thomas, Sandhya, Wang, Yanlin, Truong, Luan D., Dryer, Stuart E, Hu, Zhaoyong, Xu, Jing
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398628/
https://ncbi.nlm.nih.gov/pubmed/25641678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4508
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