Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy

In diabetic nephropathy (DN), podocyte cytoskeletal rearrangement occurs followed by podocyte effacement and the development of proteinuria. PTEN (phosphatase and tensin homolog) is a ubiquitously expressed phosphatase that plays a critical role in cell proliferation, cytoskeletal rearrangement and...

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Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Lin, Jamie, Shi, Yuanyuan, Peng, Hui, Shen, Xiaojie, Thomas, Sandhya, Wang, Yanlin, Truong, Luan D., Dryer, Stuart E, Hu, Zhaoyong, Xu, Jing
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398628/
https://ncbi.nlm.nih.gov/pubmed/25641678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4508
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