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Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy
In diabetic nephropathy (DN), podocyte cytoskeletal rearrangement occurs followed by podocyte effacement and the development of proteinuria. PTEN (phosphatase and tensin homolog) is a ubiquitously expressed phosphatase that plays a critical role in cell proliferation, cytoskeletal rearrangement and...
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| Publicado no: | J Pathol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398628/ https://ncbi.nlm.nih.gov/pubmed/25641678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4508 |
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