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Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy

Rho family GTPases are molecular switches best known for their pivotal role in dynamic regulation of the actin cytoskeleton. The prototypic members of this family are Cdc42, Rac1, and RhoA; these GTPases contribute to the breakdown of glomerular filtration and the resultant proteinuria, but their fu...

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Bibliografiset tiedot
Päätekijät: Scott, Rizaldy P., Hawley, Steve P., Ruston, Julie, Du, Jianmei, Brakebusch, Cord, Jones, Nina, Pawson, Tony
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380653/
https://ncbi.nlm.nih.gov/pubmed/22518006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121206
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