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The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro

The Rho GTPase Cdc42 is overexpressed and hyperactivated in breast cancer, and several studies have described mechanisms by which it may promote tumor formation and progression. However, little is known about the role of Cdc42 during normal mammary epithelial cell (MEC) morphogenesis. Here we aimed...

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Hlavní autoři: Bray, Kristi, Brakebusch, Cord, Vargo-Gogola, Tracy
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265815/
https://ncbi.nlm.nih.gov/pubmed/22292127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.5.18163
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