Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration

INTRODUCTION: The Rho GTPase Cdc42 is overexpressed and hyperactivated in breast tumors compared to normal breast tissue. Cdc42 regulates key processes that are critical for mammary gland morphogenesis and become disrupted during the development, progression, and metastasis of breast cancer. However...

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Bibliografski detalji
Glavni autori: Bray, Kristi, Gillette, Melissa, Young, Jeanette, Loughran, Elizabeth, Hwang, Melissa, Sears, James Cooper, Vargo-Gogola, Tracy
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978759/
https://ncbi.nlm.nih.gov/pubmed/24074261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3487
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