Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration

INTRODUCTION: The Rho GTPase Cdc42 is overexpressed and hyperactivated in breast tumors compared to normal breast tissue. Cdc42 regulates key processes that are critical for mammary gland morphogenesis and become disrupted during the development, progression, and metastasis of breast cancer. However...

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Autors principals: Bray, Kristi, Gillette, Melissa, Young, Jeanette, Loughran, Elizabeth, Hwang, Melissa, Sears, James Cooper, Vargo-Gogola, Tracy
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978759/
https://ncbi.nlm.nih.gov/pubmed/24074261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3487
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