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Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy
Rho family GTPases are molecular switches best known for their pivotal role in dynamic regulation of the actin cytoskeleton. The prototypic members of this family are Cdc42, Rac1, and RhoA; these GTPases contribute to the breakdown of glomerular filtration and the resultant proteinuria, but their fu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380653/ https://ncbi.nlm.nih.gov/pubmed/22518006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121206 |
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