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Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy

Rho family GTPases are molecular switches best known for their pivotal role in dynamic regulation of the actin cytoskeleton. The prototypic members of this family are Cdc42, Rac1, and RhoA; these GTPases contribute to the breakdown of glomerular filtration and the resultant proteinuria, but their fu...

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書誌詳細
主要な著者: Scott, Rizaldy P., Hawley, Steve P., Ruston, Julie, Du, Jianmei, Brakebusch, Cord, Jones, Nina, Pawson, Tony
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380653/
https://ncbi.nlm.nih.gov/pubmed/22518006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121206
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